Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 1% | ||||
5 tube | 1% | £37.96 | £7.59 | |
4 tube | 1% | £35.72 | £8.93 | |
3 tube | 1% | £31.26 | £10.42 | |
2 tube | 1% | £23.81 | £11.90 | |
Dosage: 5% | ||||
5 tube | 5% | £93.04 | £18.61 | |
4 tube | 5% | £80.39 | £20.10 | |
3 tube | 5% | £66.99 | £22.33 | |
2 tube | 5% | £52.10 | £26.05 |

Fluorouracil Description
Overview of Fluorouracil
Fluorouracil, also known as 5-FU, is a widely used chemotherapy medication primarily employed in the treatment of various types of cancer. This synthetic drug belongs to the class of antimetabolites, which work by interfering with the DNA and RNA synthesis in rapidly dividing cancer cells. Its effectiveness has been established over many years, making it a cornerstone in cancer treatment protocols.
Mechanism of Action
Fluorouracil works through a process called antimetabolite activity. Once administered, it is converted inside the cells into active metabolites that inhibit thymidylate synthase, an enzyme essential for DNA replication. As a result, the production of DNA is hindered, leading to the death of cancerous cells. This mechanism makes Fluorouracil particularly effective against tumors that rely on rapid cell division, such as colorectal, breast, and stomach cancers.
Forms of Administration
This medication can be administered in different forms depending on the type of cancer being treated. It is available as an injection for intravenous use, which ensures direct delivery into the bloodstream. In some cases, topical formulations containing Fluorouracil are prescribed for skin-related cancers or precancerous conditions like actinic keratosis. The dosing and frequency are carefully determined by the healthcare provider based on individual patient needs.
Effectiveness and Benefits
Patients often find Fluorouracil to be a valuable part of their cancer treatment regimen due to its proven efficacy. When used in combination with other chemotherapeutic agents or radiation therapy, it can significantly improve treatment outcomes. Its ability to target cancer cells selectively, while sparing most healthy tissues, contributes to its role as a mainstay in oncology. Many patients experience remission or significant reduction in tumor size after undergoing treatment with Fluorouracil.
Possible Side Effects
Like all chemotherapy drugs, Fluorouracil can cause a range of side effects. Common adverse reactions include nausea, vomiting, mouth sores, and diarrhea. Some patients might experience more severe effects such as bone marrow suppression, leading to lower blood cell counts and increased risk of infections. Skin reactions, including redness or rash, may also occur with topical forms. It is important for patients to be monitored regularly to manage any adverse effects promptly and effectively.
Precautions and Considerations
Before starting treatment with Fluorouracil, patients should inform their healthcare provider about any allergies, existing health conditions, or medications they are taking. This medication requires careful dosing and monitoring to prevent toxicity. Pregnant or breastfeeding women should avoid using Fluorouracil unless specifically directed by a doctor, as it may harm the developing fetus or nursing infant. Additionally, patients should report any unusual symptoms immediately during therapy.
Conclusion
Overall, Fluorouracil remains a vital component of cancer therapy thanks to its proven efficacy and targeted action. When used correctly under medical supervision, it offers significant hope for managing various tumors. As with all potent medications, understanding its benefits and risks is crucial for achieving the best possible outcomes. Its role in oncology continues to evolve, with ongoing research exploring new ways to optimize its use and minimize side effects.