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This page provides general information about Colofac and mebeverine. It is not a substitute for professional medical advice.

What is Colofac?

Colofac is a brand name for the medicine mebeverine hydrochloride. It belongs to a group of medicines called antispasmodics, used to help relieve stomach cramps and gut spasms that can occur with irritable bowel syndrome (IBS).

The tablets act mainly in the gut, helping the smooth muscles to relax. By reducing spasm, Colofac can lessen the intensity of abdominal cramps and discomfort that some people experience after meals or during flare-ups.

Colofac is intended for adults, and in some cases may be suitable for children if advised by a clinician. The exact product strength or formulation can vary, so follow the packaging or your clinician’s instructions carefully.

In the United Kingdom, whether Colofac is available over the counter or by prescription may depend on local rules and the specific product you have. If you are unsure about suitability or how to take it, ask a pharmacist or doctor for guidance.

If your IBS symptoms are new, changing, or you have other health concerns, do not rely on Colofac alone. A clinician can help determine whether this medicine is appropriate for your situation and discuss other management options.

What is Colofac used for?

Colofac is used to relieve symptoms caused by gut muscle spasm, such as abdominal cramps, pain, and discomfort in irritable bowel syndrome. It may also help with bloating that is linked to IBS in some people.

It is a symptom-relieving medicine rather than a cure for IBS. For many people it fits as part of a broader plan that can include diet changes, regular exercise, stress management, and other treatments advised by a clinician.

Colofac should be used as directed by a healthcare professional or according to the label. If you are unsure about whether it is suitable for you, speak to a pharmacist for guidance before starting treatment.

If your symptoms persist or worsen after a short course, a clinician should review your condition. Do not use Colofac to treat conditions that do not relate to IBS without medical advice.

Colofac is one part of IBS management. Your clinician may suggest other medicines or tests if symptoms continue despite treatment. Always follow the plan agreed with your healthcare professional.

How Colofac works

Mebeverine is a local-acting antispasmodic. It works mainly in the gut to relieve the tummy muscles that tighten during cramps and spasm.

By relaxing these smooth muscles, Colofac can reduce the intensity and frequency of abdominal cramps. This can lead to more comfortable periods and fewer interruptions to daily activities caused by IBS symptoms.

The effect is largely local to the gut, so it is designed to limit systemic exposure. This can help explain why many people tolerate Colofac well, though side effects can still occur in a small number of individuals.

Colofac does not address the underlying causes of IBS and is not a cure. If symptoms are persistent or changing, a clinician may review the diagnosis and consider additional strategies alongside Colofac.

As with all medicines, individual response varies. If you have questions about how Colofac works for you, talk to a pharmacist or doctor who can explain what to expect and when to seek advice if symptoms do not improve.

How to use Colofac

Read the patient information leaflet that comes with your product before you start taking Colofac. The leaflet provides guidance tailored to the exact formulation you have.

Take Colofac tablets with a full glass of water. Do not chew or crush tablets unless the leaflet explicitly allows this form of administration.

Take Colofac after meals or as directed by your clinician. Do not take more often or in larger amounts than advised on the packaging or by your healthcare professional.

If you miss a dose, take it as soon as you remember unless it is nearly time for the next dose. Do not double up to make up for a missed dose without checking with a pharmacist or doctor.

Store Colofac at room temperature, away from moisture and heat. Keep it in its original packaging to protect from light and moisture, and dispose of any out-of-date medicine safely.

Who should avoid Colofac?

Do not take Colofac if you know you are allergic to mebeverine or any other ingredient in the product. Signs of an allergic reaction include rash, itching, swelling, or trouble breathing. If these occur, seek medical help promptly.

Tell your clinician if you are pregnant, planning a pregnancy, or breastfeeding. The safety of Colofac during pregnancy and while breastfeeding is not established in all situations, so a clinician will weigh benefits and risks for you.

Colofac is not usually recommended for children unless advised by a clinician. If a child requires treatment for gut symptoms, seek advice from a pediatric specialist or your GP.

Discuss any bowel problems you have, such as a blockage, severe constipation, or persistent symptoms. Colofac may not be suitable in certain conditions, and specialist advice may be needed.

Always tell your doctor or pharmacist about all medicines you take, including non-prescription medicines, herbal products, and supplements. They can check for potential interactions and advise you on safe use.

Warnings

Keep Colofac out of reach of children and do not share your medicine with others. Use it only as directed for your own health needs.

If symptoms do not improve after a short course, or if new symptoms appear, arrange a review with a healthcare professional. They may adjust treatment or investigate further to understand the cause of your symptoms.

Be aware that Colofac can interact with other medicines and foods. Always tell your pharmacist about any medicines you are taking, including vitamins, supplements, and herbal products.

Seek urgent medical help if you notice signs of a serious allergic reaction or a new, unusual, or persistent reaction such as severe skin rash, swelling of the face or throat, or jaundice. Stop taking Colofac if advised by a clinician to do so.

It is important to monitor for unusual symptoms and report them promptly to a clinician, especially if you have liver problems or take medicines that could affect the liver or gut. Your clinician may adjust therapy based on your experience and medical history.

Side effects

Common side effects include mild digestive upset, such as nausea, flatulence, or a temporary change in bowel habit. These effects are usually mild and short-term.

Some people may feel dizzy, lightheaded, or have headaches after taking Colofac. If these effects persist or are troublesome, discuss them with a pharmacist or doctor.

Allergic reactions can occur in rare cases. Look out for a skin rash, itching, swelling, or with breathing difficulties. If these occur, seek medical help promptly.

Very rarely Colofac can affect the liver or cause unusual tiredness, dark urine, or pale stools. If you notice these signs, contact your clinician right away.

Most people tolerate Colofac well, but if you develop any other symptoms that concern you while using this medicine, contact a healthcare professional for advice and do not ignore new or worsening symptoms.

Interactions

Colofac can interact with other medicines. It is important to tell your pharmacist about all medicines you take, including non-prescription drugs and herbal products.

Some medicines may affect how Colofac works or increase the risk of side effects. Do not start or stop medicines without discussing it with a clinician who knows your full medical history.

If you are taking medicines that slow gut movement, alter bowel function, or affect the liver, talk with your doctor about whether Colofac is appropriate for you. They may adjust treatment or monitoring plans.

Always bring an up-to-date list of your medicines to healthcare appointments. If you notice any new symptoms after starting a new medicine, seek advice promptly.

Specific interactions depend on your overall health, other medications, and the exact Colofac formulation. Your pharmacist can provide a personalised check based on your situation.

Pregnancy

The safety of Colofac during pregnancy has not been established in all situations. If you are pregnant or planning to become pregnant, discuss this with your doctor or pharmacist before using Colofac.

In some cases, a clinician may decide that the benefits of continuing treatment outweigh potential risks. Do not start Colofac during pregnancy without professional advice.

If you are breastfeeding, talk to your clinician about the risks and benefits of using Colofac. Some medicines pass into breast milk, and your doctor can help you weigh options.

Always follow the guidance of a healthcare professional during pregnancy or while breastfeeding. If you experience any new symptoms or concerns, report them to your clinician promptly.

Colofac may be an appropriate choice for some pregnant or breastfeeding individuals under medical supervision, but safety depends on individual circumstances. Seek personalised advice before use.

FAQ

Below are common questions people have about Colofac. If your question is not listed, ask a pharmacist or doctor for guidance.

How quickly does Colofac start to work?

Many people notice some relief within hours or after a few days of starting treatment, especially for cramps and spasms. Others may take longer to respond. If no improvement occurs after a short course or symptoms worsen, seek medical advice.

Colofac works by relaxing gut muscles, but individual response varies. It is often used as part of a broader IBS management plan, including diet and lifestyle changes.

What should I do if I forget a dose?

Take the missed dose as soon as you remember, unless it is close to the time of your next dose. Do not double the dose to make up for a missed one. If you are unsure, seek advice from a pharmacist or doctor.

After a missed dose, resume your normal timing unless instructed otherwise by a clinician. Keep a regular schedule to help with symptom control.

Can Colofac be used with other IBS treatments or medicines?

Colofac can be used alongside other IBS management strategies, such as dietary changes or certain other medicines, if advised by a clinician. Always tell your pharmacist about all medicines you are taking.

Some combinations may require monitoring or adjustments. Your clinician or pharmacist can check for potential interactions and guide you on safe use.

How long should I use Colofac for symptoms?

Use Colofac for as long as it is advised by your clinician. If symptoms persist or recur after stopping, a review with a healthcare professional is recommended.

Do not continue to use Colofac beyond the advised period without professional input. If you have ongoing IBS symptoms, a broader assessment may be needed.

What should I do if my symptoms do not improve?

If IBS symptoms do not improve, or if you develop new or worsening symptoms, arrange a review with a healthcare professional. They may reassess the diagnosis, adjust treatment, or propose additional tests.

Persistent symptoms can have various causes, so a clinician will consider the full clinical picture before making changes to treatment.

Can Colofac be taken during pregnancy or breastfeeding?

Pregnancy and breastfeeding require careful consideration. Speak with a clinician before using Colofac if you are pregnant, planning pregnancy, or breastfeeding. They can discuss potential risks and benefits for you and your baby.

If there is a need to manage IBS symptoms during pregnancy or after birth, your clinician may suggest alternative strategies or monitor you more closely.

Can I drink alcohol while taking Colofac?

Alcohol is not known to interact strongly with Colofac in most people, but IBS symptoms can be affected by alcohol. If you notice worsened symptoms after drinking, adjust your intake and discuss it with a clinician.

For many individuals, limiting alcohol while managing IBS can help with overall symptom control and wellbeing.

Is Colofac safe for children?

Colofac may be used in children only under the direction of a clinician. The safety and appropriate dose depend on age, weight, and the child’s health history.

If a child needs treatment for IBS symptoms, a pediatrician or child-focused gastroenterologist can provide guidance tailored to the child’s needs.

What should I do if I experience side effects?

If you develop side effects, start by checking they are not a sign of a more serious condition. For mild side effects, your pharmacist or doctor can advise on remedies or whether to stop the medicine.

Seek medical help promptly if you experience signs of a serious allergic reaction or any new, persistent, or worsening symptoms.

Can I take Colofac if I have liver problems?

People with liver problems should discuss Colofac use with a clinician. The safety and suitability may depend on the extent of liver impairment and other medications you take.

Your clinician may decide to monitor you more closely or adjust your treatment plan if liver concerns exist.

What happens if I overdose or take too much Colofac?

If you think you have taken more Colofac than directed, seek medical advice promptly. Do not wait to see if symptoms develop, as an overdose should be assessed by a professional.

In an emergency, contact your local emergency service for guidance. Do not rely on home remedies to manage an overdose.

Where can I find more information?

Ask your pharmacist for the official patient information leaflet that comes with Colofac. The leaflet provides details tailored to the exact product you have.

Your GP or gastroenterology clinician can explain how Colofac fits into your IBS management plan and answer specific questions about your health history.

Sources

The information in this page is drawn from official patient information leaflets for Colofac (mebeverine) and standard guidance used by UK healthcare professionals. It reflects common, general considerations for IBS management and Colofac use.

For personalised advice, always consult your doctor or pharmacist. If you have questions about how Colofac applies to your health, a professional can review your medical history and provide tailored guidance.

Because product formulations and local rules can vary, check the packaging and speak with a pharmacist to confirm the exact instructions for the Colofac product you are using. Your clinician may adapt advice based on your individual needs.

In all cases, this information should be read alongside the official product leaflet and the care plan agreed with your healthcare professional. If in doubt, seek professional medical advice before starting or continuing Colofac.