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| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 25mg | 360 pill | £0.48 | £215.99 £172.79 Best Price | |
| 25mg | 270 pill | £0.49 | £166.14 £132.91 | |
| 25mg | 180 pill | £0.52 | £117.57 £94.06 | |
| 25mg | 120 pill | £0.58 | £86.90 £69.52 | |
| 25mg | 90 pill | £0.63 | £71.56 £57.25 | |
| 25mg | 60 pill | £0.70 | £52.39 £41.91 | |
| 25mg | 30 pill | £0.75 | £28.11 £22.48 | |
| 50mg | 360 pill | £0.64 | £290.12 £232.09 | |
| 50mg | 270 pill | £0.67 | £227.49 £181.99 | |
| 50mg | 180 pill | £0.71 | £158.47 £126.78 | |
| 50mg | 120 pill | £0.78 | £116.30 £93.04 | |
| 50mg | 90 pill | £0.84 | £94.57 £75.65 | |
| 50mg | 60 pill | £0.94 | £70.28 £56.23 | |
| 50mg | 30 pill | £1.02 | £38.33 £30.66 | |
| 100mg | 360 pill | £0.95 | £428.15 £342.52 Popular | |
| 100mg | 270 pill | £1.02 | £345.08 £276.06 | |
| 100mg | 180 pill | £1.07 | £241.55 £193.24 | |
| 100mg | 120 pill | £1.18 | £176.37 £141.09 | |
| 100mg | 90 pill | £1.25 | £140.58 £112.46 | |
| 100mg | 60 pill | £1.30 | £97.12 £77.70 | |
| 100mg | 30 pill | £1.46 | £54.95 £43.96 |
Disclaimer: This information is for general guidance only and does not replace professional medical advice. Always consult a healthcare professional for advice tailored to you.
Zoloft is the brand name for sertraline, a medicine that belongs to the selective serotonin reuptake inhibitor (SSRI) class. It is used to help restore balance in brain chemicals that can affect mood and anxiety.
It is typically prescribed to treat conditions that affect mood and emotions, such as depression and anxiety disorders. The exact use depends on your symptoms and medical history, and it should be decided by a clinician or pharmacist in line with local rules.
In the United Kingdom, Zoloft may require a prescription depending on local rules. The medicine is usually given as tablets containing sertraline and inactive ingredients. Always follow the advice of your doctor or pharmacist about how to take it and how long to continue treatment.
Keep Zoloft out of reach of children and store it in a safe place at room temperature, away from direct heat and moisture. If you have questions about whether this medicine is right for you, ask your doctor or pharmacist for information from the official patient leaflet.
Zoloft is prescribed for a range of conditions that affect mood, thinking, and behaviour. It can help reduce symptoms such as sadness, worry, and fear that interfere with daily life. Your clinician will decide if this medicine is appropriate for you based on your symptoms and history.
Common indications include mood disorders and anxiety-related conditions. It may also be prescribed for other conditions when a clinician determines it could help. The official listing of approved uses can vary by country, so always refer to the local patient information leaflet for your region.
Typical conditions treated with sertraline include major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, and post-traumatic stress disorder. It may be used for other anxiety-related conditions as well, depending on clinical judgment.
If you are unsure whether Zoloft is approved for a specific condition in your area, check the official leaflet or speak with a healthcare professional. They can confirm whether this medicine is suitable for your needs.
Sertraline works by increasing the level of serotonin, a brain chemical connected with mood, by helping its reabsorption in nerve cells. This helps to rebalance serotonin in the brain over time.
The change in brain chemistry can reduce symptoms related to depression and anxiety. It is not a stimulant and does not have immediate effects; improvement often takes several weeks and varies between people.
The exact way Zoloft improves symptoms is not fully understood. The medicine should be used under medical supervision, with gradual assessment of its effects and any side effects.
As with all antidepressants, sertraline requires careful monitoring by a clinician. If you have questions about how this medicine might help you, discuss them with your doctor or pharmacist.
Take Zoloft exactly as prescribed by your clinician. Do not change the dose or stop taking the medicine without medical advice. Your doctor will tailor the dose to your needs and how you respond to treatment.
Swallow the tablet whole with a drink of water. It can be taken with or without food, and it is usually taken at the same time each day to maintain an even level in your body.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. If it is nearly due, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Do not stop taking Zoloft suddenly, unless instructed by your clinician. Stopping abruptly can cause withdrawal-like symptoms such as dizziness, tingling, or sleep disturbances. Your clinician may advise a gradual reduction in dose.
Limit or avoid alcohol while taking Zoloft, as alcohol can worsen side effects or mood symptoms. Tell your clinician about all medicines you take, including over‑the‑counter medicines and herbal products, to check for possible interactions.
Storage: keep the medicine in its original container, at room temperature, away from moisture and heat. Keep it out of reach of children and, if advised, away from pets. Do not use the medicine after the expiry date printed on the packaging.
Do not take Zoloft if you have a known allergy to sertraline or any ingredients in the tablet. Severe allergic reactions require prompt medical attention.
Do not use sertraline together with monoamine oxidase inhibitors (MAOIs) or within a certain time window after stopping an MAOI. Your clinician will provide guidance if you have taken these medicines previously.
If you have a history of manic episodes or bipolar disorder, tell your clinician. Some people with these conditions may be more likely to experience mood changes while taking an SSRI.
If you have severe liver or kidney problems, discuss with your clinician before starting Zoloft. Your dose or treatment plan may need adjustment or closer monitoring.
If you are under 18 years of age, speak with a clinician about the benefits and risks. In many cases, sertraline is prescribed selectively for certain conditions after careful evaluation. Check local guidelines and leaflets for age-specific information.
Sertraline can interact with other medicines and substances. Always tell your clinician about all medicines you are taking to minimise the risk of interactions, including supplements and herbal products.
Serotonin syndrome is a rare but serious condition that can occur with sertraline, especially when combined with other medicines that influence serotonin levels. Seek urgent medical help if you experience high fever, fast heart rate, confusion, abnormal sweating, muscle stiffness, or agitation.
Antidepressants such as Zoloft may increase thoughts of self-harm or suicide in some younger people during the initial weeks of treatment or when the dose changes. Immediate medical attention should be sought if you notice new or worsening depression, anxiety, or unusual thoughts or behaviour.
There is a risk of increased bleeding in some people when sertraline is taken with non-steroidal anti-inflammatory drugs (NSAIDs), anticoagulants, or certain other medicines. Discuss any concerns with your clinician and follow their guidance on use of these medicines together.
Hyponatremia (low blood sodium) is possible, especially in older adults. Tell your clinician if you have symptoms such as confusion, difficulty concentrating, loss of energy, or seizures.
Most people tolerate Zoloft well, but some experience side effects. Many side effects occur early in treatment and may improve with time. If side effects are persistent or bothersome, talk with your clinician.
Common side effects include upset stomach, nausea, dry mouth, sleep disturbances (insomnia or drowsiness), increased sweating, and mild dizziness. Some people notice changes in sexual function or appetite while taking sertraline.
Explain any persistent or worrying symptoms to your clinician. If you notice signs of a severe allergic reaction, sudden swelling, or trouble breathing, seek urgent medical help.
Sertraline can interact with other medicines. Some combinations can change how well medicines work or increase the risk of side effects. Always inform your clinician about all medicines you use, including over‑the‑counter products and herbal remedies.
Medicines that can interact with sertraline include other antidepressants, certain pain relievers, and medicines that affect serotonin levels. It is especially important to avoid combining Zoloft with MAO inhibitors unless guided by a clinician.
If you are taking anticoagulants or NSAIDs, discuss the risk of bleeding with your clinician. They may adjust treatment or monitoring as needed. Do not start, stop, or change other medicines without advice from a healthcare professional.
Pregnancy planning and use of Zoloft during pregnancy should be discussed with a clinician. The decision to use this medicine in pregnancy is made by weighing the benefits to the mother against potential risks to the baby.
Breastfeeding is possible in some cases, but sertraline passes into breast milk. A clinician can help determine whether the benefits to the mother outweigh any potential risk to the infant and may suggest monitoring or alternative options.
If you are pregnant or planning pregnancy, or if you are currently breastfeeding, talk to your clinician before continuing or starting Zoloft. Do not stop taking the medicine without medical advice, as this may affect your condition and the baby's health.
For any questions about safety during pregnancy or while breastfeeding, check the official patient information and discuss with your physician or pharmacist.
Many people begin to notice some improvement after a few weeks, but it can take longer for others. It is common for the full benefit to develop over several weeks of consistent use. Do not expect immediate results and discuss progress with your clinician at follow-up appointments.
If you remember soon after a missed dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed one. If you frequently forget doses, talk to your clinician about a plan to help you stay on track.
Alcohol can worsen some side effects and may affect mood and effectiveness. It is usually best to limit or avoid alcohol while taking this medicine, unless advised otherwise by your clinician.
Sertraline is not considered addictive in the same way as substances like alcohol or nicotine. However, stopping suddenly can cause withdrawal-like symptoms in some people. If you need to stop, a clinician can guide a gradual taper to minimise these effects.
Some medicines interact with sertraline. Always tell your clinician about all medicines you take, including over‑the‑counter drugs and supplements. Do not start or stop medicines without professional guidance.
Common side effects include nausea, dry mouth, sleep changes (insomnia or sleepiness), sweating, and mild dizziness. Some people also experience changes in sexual function or appetite. Most side effects improve with time or adjusting the dose under medical supervision.
Seek urgent medical help if you have signs of a serious reaction, such as severe hives, swelling, trouble breathing, sudden severe headache, high fever, or confusion. If you notice new or worsening thoughts of self-harm, contact a clinician promptly.
Sertraline may be prescribed to younger people for certain conditions after careful evaluation. The safety and effectiveness can vary by age and condition. Please discuss with a clinician who can review the individual circumstances.
Stopping suddenly can cause withdrawal-like symptoms for some people. If you need to stop, your clinician will usually plan a gradual reduction in dose. Do not stop without medical advice.
Pregnancy and breastfeeding involve careful risk assessment. A clinician will consider the benefits to the mother and potential risks to the baby, and may suggest alternatives or closer monitoring. Do not change treatment without advice from a healthcare professional.
Store at room temperature, away from light and moisture. Keep the medicine in its original packaging and out of reach of children. Do not use it after the expiry date printed on the packaging.
The information in this page draws on general patient information about sertraline. For the most accurate and region-specific details, refer to the official patient information leaflet provided with your medicine and consult a healthcare professional.
In the United Kingdom context, you may also consult the NHS information on antidepressants and the Medicines and Healthcare products Regulatory Agency (MHRA) guidance for antidepressants, as well as your local pharmacy’s advice. Always rely on the official leaflet and your clinician for dosing, duration, and safety guidance.
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